Korean-Origin Technology · Polynucleotide Skincare
Rejuran® Singapore
Needle-Free PDRN Facial
Acne Scar Treatment · Glass Skin · Skin Rejuvenation Singapore
Rejuran® c-PDRN — salmon-derived polynucleotide technology from Korea — is designed to support the skin's own repair. At SkinRev, we deliver it topically using Meso Touch transdermal technology: PDRN skincare without needles, with little to no downtime.
What Rejuran actually is
Rejuran is a Korean brand of polynucleotide, usually written PDRN. Polynucleotides are short chains of DNA fragments, in Rejuran's case purified from salmon, which are close enough to human DNA to be well tolerated and which signal skin to repair itself — supporting fibroblast activity, collagen renewal, hydration and barrier quality.
It is not a laser, a machine or a filler. Nothing is added to fill a line and nothing is heated. What changes the result is how much polynucleotide reaches living skin, and by which route it gets there.
Quick answer
- The Rejuran® PDRN Facial is a needle-free facial using cosmetic-grade c-PDRN, a salmon-derived polynucleotide, delivered with Meso Touch transdermal technology.
- It suits clients wanting better skin quality and hydration, or calmer post-acne and sensitised skin, who prefer to avoid injections.
- Sessions run 60, 75 or 90 minutes depending on the protocol; there is usually no recovery period, and a course is planned at your assessment.
- Performed by our Aesthetic Specialists at SkinRev Lab, CityLink Mall #B1-28, linked underground to City Hall MRT.
“Rejuran is an ingredient story, not a machine story. The honest question is not which clinic has the best device — it is how much polynucleotide reaches living skin, and by what route.”
SkinRev Lab Aesthetic Specialist
Two routes: injected, and needle-free
Injected. Professional-grade PDRN placed intradermally with a fine needle. This is a medical procedure. In Singapore it must be performed by a licensed doctor, it uses a higher concentration, it reaches the deepest, and it carries the trade-offs of an injection — mild pain, temporary papules, redness and usually one to three days before skin looks settled.
Needle-free. Cosmetic-grade c-PDRN delivered transdermally — past the stratum corneum, without breaking the skin. No needles, no bruising, little to no downtime, and it can be repeated comfortably. The concentration is lower than the injectable and the change is gradual rather than immediate, which is why it is done as a course rather than a one-off.
Neither route is a substitute for the other. They sit at different points on the same line, and the right one depends on how much correction you actually want and how much recovery time you are willing to give it.
What SkinRev Lab does — and what it does not
SkinRev Lab is a non-invasive aesthetic centre, not a clinic. We do not inject, and we will not tell you otherwise. Our Rejuran PDRN Facial uses cosmetic-grade c-PDRN delivered transdermally through Meso Touch, performed by our Aesthetic Specialist.
If what you want is an injectable polynucleotide treatment, that is a doctor's procedure and we will say so on the day rather than sell you something else. If what you want is the polynucleotide benefit without needles, bruising or a recovery window — that is precisely what this is.
Injected vs needle-free, side by side
| Needle-free c-PDRN facial (SkinRev Lab) | Injectable Rejuran (medical clinic) | |
|---|---|---|
| Where it is done | Aesthetic centre | Licensed medical clinic |
| Who performs it | Aesthetic Specialist | Licensed doctor |
| Needles | None — transdermal delivery | Fine needle, intradermal |
| Grade of PDRN | Cosmetic-grade c-PDRN | Professional-grade, higher concentration |
| Downtime | Little to none | 1–3 days of papules and redness |
| How results arrive | Gradually, across a course | Faster and stronger |
| Suitable for | All skin types, including sensitive | Adults without contraindications |
| Offered at SkinRev Lab | Yes | No — this is a doctor's procedure |
The Science
What Is PDRN and
Why Does It Work?
Polynucleotides (PDRN) are long-chain DNA fragments derived from salmon sperm DNA — which is close enough to human DNA to be well tolerated. When absorbed into the skin, they activate specific repair receptors (A2A adenosine receptors), triggering fibroblast proliferation, collagen synthesis, and anti-inflammatory cascades. The aim is to support the skin's own renewal from within.
Comparison
Rejuran® Topical vs
Other Facial Approaches
Understanding what sets the Rejuran® PDRN facial apart helps clarify whether it's right for your skin goals and skin type.
| Feature | Rejuran® PDRN Facial (SkinRev) | Traditional Facial | Medical Injectable PDRN |
|---|---|---|---|
| Needles / Pain | No needles, comfortable | No needles | Injections required, mild pain |
| Downtime | Little to none | Little to none | 1–3 days (papules, redness) |
| Active Ingredient | Cosmetic c-PDRN polynucleotides | Standard skincare actives | Professional-grade PDRN (higher concentration) |
| Skin Repair Depth | Transdermal — beyond stratum corneum | Surface only | Intradermal — deepest penetration |
| Provider Required | Aesthetic therapist (SkinRev) | Aesthetic therapist | Licensed medical doctor |
| Collagen Stimulation | Yes — biostimulatory | Minimal | Yes — stronger effect |
| Suitable For | All skin types incl. sensitive | Most skin types | Adults without contraindications |
Treatment Menu
Choose Your
Rejuran® Protocol
SkinRev offers three Rejuran® protocol tiers, each building on the last. Your therapist will recommend the most appropriate starting point during your skin assessment.
- Double cleanse + enzyme exfoliation
- Skin analysis and concern mapping
- Meso Touch c-PDRN infusion
- Hyaluronic acid moisture seal
- SPF finish and recovery guidance
- Everything in Rejuran® Essential
- Ultrasound enhancement for deeper delivery
- Targeted brightening booster serum
- LED red light therapy (collagen stimulation)
- Skin Yoga EMS microcurrent lift
- Everything in Rejuran® Pro
- Exosome repair booster complex
- Lymphatic drainage and contouring massage
- Eye zone peptide treatment
- Scalp care and stress release protocol
What to Expect
Results That Build
Session by Session
The Rejuran® PDRN facial is designed for progressive results. Skin often looks more hydrated after a session; deeper changes build over a series. Individual results vary.
Your Skin. Visible Results.
"The glass skin effect is real. I combine monthly Rejuran® with HydraFacial every two months and my skin has never looked better. The team at CityLink Mall is knowledgeable and professional every time."
Jasmine L.
Rejuran® + HydraFacial Protocol
“ HydraFacial is for a quick reset with little to no downtime; Rejuran is for longer-term skin quality built over a course. — Our Aesthetic Specialist, SkinRev Lab
What Does Your Skin Need?
Answer 3 quick questions and we'll recommend the best facial — and any supporting modalities — for your skin right now.
Step 1 of 3
What bothers your skin most?
Select all that apply.
Step 2 of 3
How long have you had these concerns?
This helps us understand how established your skin issues are.
Step 3 of 3
How sensitive is your skin?
This guides the intensity and approach of your protocol.
Your Skin Protocol
Based on your skin profile…
Recommendations are indicative. A clinical consultation at SkinRev will confirm the best protocol for your skin.
What Is Your Skin Telling You?
Rate each skin signal over the past month. 8 questions · 80 points total · your Skin Renewal Tier revealed instantly.
1 = poor recovery / persistent redness · 10 = skin bounces back well
How quickly does your skin recover from stress or irritation?
Presence of redness, scarring or post-inflammatory marks
1 = significant fine lines / loss of firmness · 10 = firm, youthful skin
Visible fine lines, wrinkles or skin laxity
Skin elasticity and bounce-back when pinched
1 = dull, tired, uneven · 10 = glowing, even, luminous
Overall skin radiance and glass-skin effect
Skin tone evenness and dark spot presence
1 = compromised barrier / dehydrated · 10 = strong barrier, well-hydrated
Skin barrier integrity — stinging, flaking or tightness
Skin plumpness and moisture retention through the day
Questions
Frequently Asked
Questions
Begin Your Glass Skin Journey
Rebuild From Within.
No Needles. Little Downtime.
Korean PDRN technology. Delivered topically. Progressive results; individual results vary.
Powered by Rejuran® Professional
SkinRev exclusively uses the Rejuran® Professional range — a widely used South Korean PDRN range, with patented DOT™ (DNA Fragments Optimizing Technology).

Core Protocol
Healing Essence
2% Hydrolyzed DNA for visible skin repair and luminosity.

Brightening
Skin Booster
Improves skin tone and supports collagen production.

Radiance
Tone-Up Booster
Revives dull skin with brightening and PDRN technology.

Full Regimen
Healing Care Set
Five-piece regimen for radiant, youthful skin post-treatment.

